Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 4th International conference on Diabetes, Hypertension and Metabolic Syndrome Osaka, Japan.

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Scientific Program Day 1

Day :

  • Basic & Translational Diabetes Research

Session Introduction

Shula Shazman

The Open University of Israel, Israel

Title: Selecting Intermittent Fasting Type to Improve Health in Type 2 Diabetes: A Machine Learning Approach
Biography:

Shula Shazman received her B.Sc. in Computer Sciences from the Technion, Israel in 1993.
In 2011 she has finished her M.Sc. + Ph.D. in Biological Sciences, In the faculty of biology, at the Technion, Israel. The title of thesis is 'Computational approaches for characterizing Protein-Nucleic-Acid Binding'. 
During 2011–2015 she has been a postdoctoral fellow in the Department of Biochemistry & Molecular Biophysics, Columbia University, New-York, USA. 
Currently Shula works at the Department of Mathematics and Computer Science, The Open University of Israel. Their current projects are 'Disordered proteins' and 'Intermittent Fasting as a tool to treat Type 2 Diabetes'.
 

Abstract:

Intermittent fasting (IF) is the cycling between periods of eating and fasting. The main types of IF are complete alternate-day fasting; time-restricted feeding (eating within specific time frames such as the most prevalent 16:8 fast, with 16 hours of fasting and 8 hours for eating); religious fasting such as the Ramadan (occurs one month per year, with eating taking place only after nightfall). IF can be effective in reducing metabolic disorders and age-related diseases by bringing about changes in metabolic parameters associated with type 2 diabetes. Questions do remain, however, about the effects of the different types of IF as a function of the age at which fasting begins, gender and severity of type 2 diabetes. In this paper we describe a machine learning approach to selecting the best type of IF to improve health in type 2 diabetes. For the purposes of

this research, the health outcomes of interest are changes in fasting glucose and insulin. The different types of intermittent fast offer promising non-pharmacological approaches to improving health at the population level, with multiple public health benefits.

Shiju Raman Unni

Al Nahdha Hospital ,Oman

Title: Management of diabetic ketoacidosis after the introduction of local hospital protocol in the secondary care hospital
Biography:

Dr.Shiju Raman unni obtained M.B.B.S from  india in 1998.He succesfully completed his M.R.C.P UK in the year 2013. He underwent endocrine and diabetes training in cardiff university UK. He also obtained speciality certificate in Endocrinology and Diabetes from RCP,UK. He pursuised MSc Diabetes from cardiff university in the year 2021 .He currently working as specialist physician ,Internal medicine ,Diabetes and Endocrinology in Al Nahdha Hospital ,Oman. He is one of the  department board member .He is invited speaker in   various scientific sessions  in both national and international conferences. He has written various hospital guidelines .He is active member in many organisations like ADA,AACE,RCP,ACP and ODA.He got poster award for his Diabetes Ketoacidosis study.He involved in various social activities conducted various free medical camps for poor people.He has published many scientific articles in international peer reviwed journals.

Abstract:

Background: Diabetic ketoacidosis (DKA) is an acute, severe and life-threatening metabolic complication of diabetes. Objective: The objective of this study was to conduct a clinical audit of the management of DKA based on the hospital protocol in the selected secondary care hospital. Design: An observational retrospective longitudinal study design was used to review the data of the patients admitted with DKA. Settings: The study was conducted in a secondary care government hospital, which has 200 beds, including 48 beds in medical ward and 6 beds in the high dependency unit. Materials and Methods: A survey questionnaire was used based on local hospital protocol, and the data was collected from patient’s admission notes between January 2010 and December 2014, using electronic patient’s records. Outcome Measures: The study looked at outcomes such as how DKA protocol was followed, complications, adherence, causes, investigations carried out or not, severity, readmissions, and duration of the stay. Sample Size: The audit selected 49 patients from a total of 83 admission notes with DKA who fits the sampling criteria. Results: Of 49 patients, 38 patients were having type 1 diabetes mellitus and 11 patients having type 2 diabetes mellitus. The most common cause in both groups is omission of insulin. Intravenous 0.9% sodium chloride was initiated in the early first hour of diagnosis of DKA for most patients. Readmission rate was 25%. Insulin was commenced in less than 1h for two-thirds of the total patients. Poor adherence to the protocol such as monitoring serum sodium bicarbonate, serum potassium levels and replacement of potassium levels in the early period of management were observed. Conclusion: Continued evidence-based practice and education for medical and paramedical staffs is needed to reduce the complications of DKA and efficiently resolve DKA, improve patient outcomes, and reduce the length of hospital stay. New DKA protocol has been introduced in the hospital as the result of this audit.

Abd Elgadir A Altoum

Gulf Medical University, Ajman, UAE

Title: Study Of Levels Of Selective Oxidative Stress Markers (Malondialdehyde, Zinc, And Antioxidant Vitamins A, E, And C) In Ischemic And Non-Ischemic Heart Disease Patients Suffering From Type- 2 Diabetes
Biography:

Objective: The objective of the current study is to compare the levels of oxidative stress markers malondialdehyde (MDA), zinc, and antioxidant Vitamins (A, E, and C) in ischemic heart disease (IHD) and non-IHD patients with diabetes mellitus.
Method: This is cross-sectional study group, conducted in the advanced diagnostic center (Khartoum- Sudan). Comprised 100 healthy subjects were, control group with mean (fasting blood sugar) 5.61=m mol/L, the age ranged from 22 to 78 years old, the average of the age was 50.1 years. 300 patients (78 IHD and 222 without) as cases groups, the ages ranged from 30 to 80 years. The age average was 51.2 years, all samples were in a state of fasting for 12 h, and the data were collected using a structured questionnaire and direct interview to collect information. Blood specimens were collected from both groups, and plasma levels of MDA, zinc, and antioxidant Vitamins (A, E, and C) were determined.
Results: There was a significant difference between the level of serum Vitamin A, E, Zinc and MDA in diabetic patients with IHD and those diabetic
without IHD (p<0.05). No significant differences in serum Vitamin C level between both groups (p>0.05).
Conclusion: Due to the significant differences in serum Vitamin A, E, Zinc, and MDA between diabetics with IHD and diabetics without IHD, these
parameters can be used as prognostic markers for prediction of oxidative stress and antioxidant stress of diabetic patients with IHD complications
 

Abstract:

Dr. Abdelgadir Elamin  is an Assistant Professor in Medical Laboratory Sciences Program of College of Health Sciences, Gulf Medical University. He has more than 15 years of teaching and research experience and published several scientific papers in reputed journals. Education B.Sc. Medical Laboratory Sciences (Clinical Chemistry) from University of Science and Technology, Sudan in 2002. M.Sc. Clinical Chemistry from Sudan University for Sciences and Technology, Sudan in 2008. Ph.D. in Clinical Chemistry from University of Science and Technology, Sudan in 2015. Research Interests focus on Oxidative stress-induced risk factors associated with the metabolic syndrome Diabetes Cardiovascular Disorders and Antioxidant

Thamer ALOhali

King Abdulaziz Medical City, Saudi Arabia

Title: Epidemiology of Diabetes and Diabetes-Related Complications in Saudi Arabia
Biography:

Thamer AlOhali is a family medicine consultant with subspecialty in public health and healthcare quality improvment. He is a consultant at King Abdulaziz Medical City, Saudi Arabia. He has completed his residency training program at Prince Sultan Military Medical City in Riyadh on 2011. He obtained his Clinical Health Care Quality and Patient Safety Fellowship in University College London Hospitals on 2014 and, on January 2016 he completed his Clinical Fellowship in Primary Care and Public Health at Imperial College London

Abstract:

Diabetes Mellitus (DM) is an increasing global health proplem. The most recent data from the World Health Organization (WHO) estimates show a global prevalence of about 422 million people worldwide have diabetes in 2020. Moreover, 1.6 million deaths are directly attributed to D.M. each year.
According to the latest information on Feburarey 2020 from the International Diabetes Federation (IDF), the prevelance of DM in Saudi Arabia is about 18.3% where the total cases in adults about 4,275,000. Based on the WHO report, Saudi Arabia ranks the second highest in the prevalence of DM in the Middle East and seventh in the world. According to the Saudi Ministry of Health (MOH), about 0.9 million people were diagnosed with diabetes in 1992, but this incidence increased to 2.5 million people in 2010. This representing approximately 2.7 times rise in the diabetes incidence rates in less than two decades.
The most important risk factors for this rapidly increasing in the incident and prevalence of DM in Saudi Arabia are lifestyle patterns and urbanization, dietary pattern, decreasing physical activity levels, obesity and ageing population. 
The estimated global direct health expenditure on DM in 2019 is $760 billion and is expected to grow to a projected $825 billion by 2030. While in Saudi Arabia, the estimated economic burden of diabetes is expected to be about $4.53 billion a year.
According to a Saudi National Diabetes Registry-based study, 10.8% of diabetics have nephropathy. Furthermore, the overall occurrence of diabetic retinopathy is about 19.7%.
 

M. Constantine Samaan

McMaster University, Canada

Title: Insights into adiposity and its determinants in survivors of childhood brain tumors: questions answered, answers questioned
Biography:

Dr. M. Constantine Samaan is a staff physician in the division of Pediatric Endocrinology and Associate Professor in the Department of Pediatrics at McMaster University and McMaster Children's Hospital.
Dr. Samaan’s research program is in the area of translational research, with specific focus on pediatric diabetes.

Abstract:

Survivors of Childhood Brain Tumors (SCBT) is an emerging population of cancer survivors, a group that now represents millions of people globally. Preliminary evidence suggested that many survivors develop cardiovascular diseases, type 2 diabetes, and obesity and that these conditions are emerging as important determinants of long-term outcomes in this group. 
 
One of the hallmarks of dysmetabolism in SCBT is increased fat mass with a similar body mass index profile to non-cancer controls. The mechanisms driving this adipose phenotype are unraveling and will create a platform for discovering therapeutic entry points in survivors to improve longevity and quality of life. 
 
This talk aims to describe the phenotypic and adipokine profile of SCBT that may predispose them to cardiometabolic risk and evaluate current therapeutic strategies and their potential impact of outcomes in survivors. 
 

Nadia BOUDJENAH

Diabetic Foot center, Algeria

Title: DIABETIC FOOT IN ALGERIA – ILLUSTRATION No II
Biography:

Nadia BOUDJENAH is affiliated from Diabetic Foot center, Algeria.

Abstract:

Our therapeutic:
- local treatments consist of a water bath and H2O2 at 10 volumes, followed by the application of LEADERMAX* (local ointment) and MAGGOT THERAPY daily until detachment or debridement.
- CARBON DIOXIDE THERAPY SESSIONS (CDT)
- Broad spectrum antibiotic therapy at first and then, targeted antibiotic therapy.
- Anticoagulants: Aspegic / Plavix, after opinions of the cardiologist and the nephrologist
- Once the maggots will have split the lesions into the area to be removed and the underlying budding due to the improved vascularity of the floor, surgical debridement was performed.
- The relay is then taken by dressings with ALTRAZEAL* and BELCIC* cream.
- Physical activity, walking with complete discharge, and anti-oedema posture.
In conclusion:
This patient, blind and victim of COVID 19, had a complication of decubitus: double pressure ulcer of the heels.
 
His treatment did not require hospitalization and complete healing was achieved within 7 months.
 
We stress the importance of the timing of the debridement, performed at 5 and 7 weeks after the first visit, to avoid worsening the lesions.
 
Vascularization was improved by CARBOMEDTHERAPY (CDT) weekly sessions at first for 2 months, and bi-monthly thereafter until healing, as evidenced by the comparative trace obtained during explorations by PERICAM.